Emergence of Advanced Antifungal-Delivery Approaches for the Treatment of Tinea Pedis

Abdalla, Ahmed; El-Sawy, Hossam Samir; Ramadan, Afaf A.

doi:10.21608/erurj.2024.227252.1064

Emergence of Advanced Antifungal-Delivery Approaches for the Treatment of Tinea Pedis

Document Type : Review articles

Authors

¹ Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 11829, Egypt

² Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt / Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy (Girls), Al- Azhar University, Cairo, Egypt

10.21608/erurj.2024.227252.1064

Abstract

A common fungal infection of the feet known as tinea pedis, which is also known as athlete's foot, significantly lowers quality of life. Its occurrence is caused by dermatophytes, a form of fungus that grows on the dead skin of the feet. Itching, scaling, redness, and skin breaking are among the symptoms that can be brought on by tinea pedis. In extreme circumstances, it may also result in nail infections and painful blisters. Antifungal medications, either systemic or topical, are widely used to treat tinea pedis. In recent years, there has been a surge in interest in developing novel medication delivery systems/strategies for the treatment of tinea pedis. By improving the drug's penetration into the skin and lowering the chance of systemic side effects, these systems seek to increase the safety and efficacy of antifungal therapy. This review has covered the many effective ways to treat tinea pedis, including traditional and state-of-the-art sophisticated delivery techniques. Furthermore, prospective avenues for treatment optimization and recurrence prevention of these severe fungal infections have been emphasized.

Keywords