Customizing Drug Therapy Based on Genetic and Molecular Information

Document Type : Mini-review

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Clinical Pharmacy and Pharmacy Practice Department, Faculty of Pharmacy, Egyptian Russian University, Badr city, Egypt

Abstract

This comprehensive review article explores the effect of personalized medicine on patient care in clinical pharmacy. Personalized medicine tailors treatments based on genetic and molecular information, recognizing individual variability in drug responses. Pharmacogenomics, a vital subfield of genomics, reveals how an individual's genetic makeup influences their response to drugs, with practical applications in various medical conditions. This study explores the significance of customizing drug therapy based on genetic and molecular information. It provides a nuanced perspective to guide clinical pharmacists in optimizing drug regimens within this evolving paradigm. The exploration is clarified through four key sections. First, it investigates the critical role of genetic and molecular information in drug therapy, emphasizing the advantages of customizing drug therapy and acknowledging the challenges in applying personalized medicine. Second, Clinical pharmacists are essential in shaping policies, promoting accessibility, and advocating for ethical practices. Third, the future of clinical pharmacy is in genomic and molecular tools, artificial intelligence, and machine learning algorithms, providing personalized, predictive, and preventive healthcare. Fourth, Case studies and success stories highlight the benefits of incorporating genetic and molecular information into routine clinical practice, showing how tailoring drug therapy based on individual genetic factors enhances treatment efficacy and improves patient outcomes.

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