Mini-review on Terminalia muelleri Benth Phytochemicals and biological activities

Document Type : Mini-review

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Cairo, Badr City 11829, Egypt./ Department of Pharmacognosy, College of Pharmacy, University of Kut, Al Kut, Wasit 52001, Iraq.

2 Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Cairo, Badr City 11829, Egypt.

Abstract

Terminalia muelleri Benth is a species of tree belonging to the genus Terminalia within the family Combretaceae. It is native to the tropical regions of northern Australia, particularly found in the savannah woodlands and open forests. This species is commonly known as the Mueller's Terminalia or the Mueller's Almond. Terminalia muelleri Benth exhibits promising medicinal properties. Traditional indigenous knowledge recognizes its various therapeutic uses, including the treatment of gastrointestinal disorders, skin infections, and inflammation. Recent scientific investigations have identified bioactive compounds in the bark, leaves, and fruits, suggesting potential pharmacological applications like antioxidant, directly neutralize free radicals, reducing oxidative stress, enhancing the activity of endogenous antioxidant enzymes like superoxide dismutase (SOD) and catalase, antimicrobial, anti-inflammatory, and hepatoprotective uses. More in-vitro studies will be needed to prove the pharmacological effect of these compounds. Continued research may bridge traditional knowledge and contemporary scientific understanding. This integration could lead to innovative treatments derived from native Australian flora.

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